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In addition, this patient additionally had polycythemia, doubtless secondary to high-dose testosterone. The patient underwent successful percutaneous intervention of the best coronary artery. Physicians and patients should be conscious of the clinical consequences of anabolic steroid abuse. Erythrocytosis has been reported as a potential effect of testosterone, which can be beneficial in sufferers with anemia.
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The greatest risk of erythrocytosis occurs with injectable types of testosterone in contrast with transdermal preparations, particularly in supraphysiologic doses. An improve of as a lot as 44% of the baseline hematocrit has been reported . Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a element of endothelial dysfunction has been proposed, which can contribute to irregular vessel reactivity. However, testosterone in physiologic doses may even be helpful in sufferers with angina , have larger ischemic thresholds and improved high quality of life .